MERCEDES-BENZ E350 · model year

2006 MERCEDES-BENZ E350

482 NHTSA complaints, 20 crash reports, and 4 active recalls for this specific cohort.

NHTSA overall rating

Not crash-tested

New Car Assessment Program

The 2006MERCEDES-BENZE350 carries 482 consumer safety complaints in NHTSA's Office of Defects Investigation database for this specific model-year cohort. Within that volume, owners reported 20 crashes, 13 fires, 36 injuries, and 3 fatalities. No NCAP 5-star crash-test rating is available for this model year in the federal database.

Component-level analysis is where model-year complaints become actionable: the top complaint category for the 2006 E350 is fuel/propulsion system with 144 filings, followed by fuel system, gasoline (75) and engine (50). Concentration in one or two component groups is the classic signature of a systemic defect; a flat distribution usually reflects normal aging, warranty complaints, or isolated build-plant variability. This model year has 4 active recall campaigns, which means the manufacturer is obligated to remedy the covered defect at no charge for the life of the vehicle — the full NHTSA campaign numbers are listed below.

NHTSA currently has 1 investigation file overlapping the 2006 E350. Owners comparing this cohort against neighboring years should pair the counters above with the complaint-by-year trend on the parent model page — a spike in a single year often tracks to a platform refresh, a new transmission supplier, or an updated ECU calibration. Use the related-complaint feed below to read raw owner narratives before deciding whether any pattern here affects your specific use case.

482
Complaints
20
Crashes
13
Fires
36
Injuries
3
Deaths

Total Complaints

482 filings

Crashes Reported

20 reports

Source

NHTSA ODI

Federal complaints database

Complaints vs. fleet median (215)

Above median complaint volume — review patterns below.

Complaints by Component

ComponentCount
FUEL/PROPULSION SYSTEM144
FUEL SYSTEM, GASOLINE75
ENGINE50
SERVICE BRAKES46
POWER TRAIN29
ELECTRICAL SYSTEM14
ENGINE AND ENGINE COOLING14
AIR BAGS11
UNKNOWN OR OTHER10
POWER TRAIN:AUTOMATIC TRANSMISSION8
VEHICLE SPEED CONTROL7
ENGINE AND ENGINE COOLING:ENGINE7
STEERING6
SERVICE BRAKES, HYDRAULIC6
TIRES5

Recalls (4)

22V95400023/12/2022

VISIBILITY:SUN/MOON ROOF ASSEMBLY

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The glass sunroof panel may not be properly secured and may detach.

19V91800020/12/2019

VISIBILITY:SUN/MOON ROOF ASSEMBLY

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2001-2011 vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly resulting in the glass panel detaching from the vehicle. For a full list of the affected models visit: https://static.nhtsa.gov/odi/rcl/

24V87400019/11/2024

VISIBILITY:SUN/MOON ROOF ASSEMBLY

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please see the recall report for a complete list of models and model years. The glass sunroof panel may not be properly secured and can detach.

21V19600019/03/2021

VISIBILITY:SUN/MOON ROOF ASSEMBLY

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2007 C350, C230, C280, CLK350, E320CDI, E350 Wagon, E350, 2006 C55 AMG, CLK500, CLS500, CLS55 AMG, E500 Wagon, E500, E55 AMG, 2007 CLK550, CLS550, CLS63 AMG, E550, E63 AMG, and E63 Wagon AMG vehicles. The bonding between the glass panel an

Recent Complaints

20251203SERVICE BRAKES

Mercedes Benz issued a recall and extended a warranty on its 2003-2005 E Class SBC braking systems (recall # 2005110001) and extended the warranty to 25 years; the 2006 E Class models have the exact same SBC braking system but is not included in the recall. Mercedes needs to add the 2006 E Class models to recall # 2005110001. My 2006 is experiencing the same SBC issues the 2003-2005 models are known to have but because my vehicle is 2006 it is not covered by the extended warranty.

20251203FORWARD COLLISION AVOIDANCE: AUTOMATIC EMERGENCY BRAKING

Mercedes Benz issued a recall and extended a warranty on its 2003-2005 E Class SBC braking systems (recall # 2005110001) and extended the warranty to 25 years; the 2006 E Class models have the exact same SBC braking system but is not included in the recall. Mercedes needs to add the 2006 E Class models to recall # 2005110001. My 2006 is experiencing the same SBC issues the 2003-2005 models are known to have but because my vehicle is 2006 it is not covered by the extended warranty.

20251023SERVICE BRAKES, HYDRAULIC

The contact called on behalf of the owner of a 2006 Mercedes-Benz E350. The contact stated that while his mother was driving at an undisclosed speed and approaching a traffic light, the brake pedal was depressed; however, the brakes failed to function as intended. The brake pedal was depressed down to the floorboard. The contact's mother used the parking brake to stop the vehicle. The ABS warning light was illuminated. The vehicle was towed to the residence and then to an independent mechanic. The vehicle was diagnosed with Sensotronic Brake Control (SBC) system failure. The contact was informed that the Sensotronic Brake Control system needed to be replaced. The vehicle remained with the mechanic unrepaired. The manufacturer was made aware of the failure and advised the contact to report the failure to the NHTSA Hotline. The failure mileage was approximately 180,000.

Mileage: 180,000

20251021VISIBILITY

The contact's son owns a 2006 Mercedes-Benz E350. The contact stated that while his son was driving at an undisclosed speed, the sunroof detached and shattered on the roadway. The vehicle was not taken to the dealer or an independent mechanic. The vehicle was not repaired. After investigating the failure, the contact related the failure to NHTSA Campaign Number: 19V918000 (Visibility) and 22V954000 (Visibility); however, the VIN was included in the recalls, but the vehicle had been repaired in 2023 and 2025. The manufacturer was not notified of the failure. The failure mileage was 97,900.

Mileage: 97,900

20250530UNKNOWN OR OTHER

Reduce power braking depress brake fully keeps popping up on my dash and not letting me take it out of gear

20240829ENGINE

The engine in these cars are defective and can cause serious harm due to a part that was put inside the motor made of plastic. There was a lawsuit but if you didn’t get in on it you losses out for not knowing. I was recently at Mercedes dealership to fix recalls and they brushed me off. The car can catch fire and I’m already experiencing engine failure after only owning the car for a year. They don’t care because it’s an old car but it’s still being sold to unsuspecting buyers. I’m not the only one there are thousands of us who are at risk driving these cars because Mercedes won’t admit their off the showroom floor mistake.

20240829POWER TRAIN

The engine in these cars are defective and can cause serious harm due to a part that was put inside the motor made of plastic. There was a lawsuit but if you didn’t get in on it you losses out for not knowing. I was recently at Mercedes dealership to fix recalls and they brushed me off. The car can catch fire and I’m already experiencing engine failure after only owning the car for a year. They don’t care because it’s an old car but it’s still being sold to unsuspecting buyers. I’m not the only one there are thousands of us who are at risk driving these cars because Mercedes won’t admit their off the showroom floor mistake.

20240829VEHICLE SPEED CONTROL

The engine in these cars are defective and can cause serious harm due to a part that was put inside the motor made of plastic. There was a lawsuit but if you didn’t get in on it you losses out for not knowing. I was recently at Mercedes dealership to fix recalls and they brushed me off. The car can catch fire and I’m already experiencing engine failure after only owning the car for a year. They don’t care because it’s an old car but it’s still being sold to unsuspecting buyers. I’m not the only one there are thousands of us who are at risk driving these cars because Mercedes won’t admit their off the showroom floor mistake.

20240321SERVICE BRAKES

The contact owns a 2006 Mercedes-Benz E350. The contact stated while driving at 35 MPH, the vehicle would not stop when depressing the brake pedal. No warning lights were illuminated, however, the contact stated the entire instrument panel was illuminated in red. The vehicle was taken to a local independent mechanic where the vehicle's brake line, brakes, and rotors were replaced. The contact stated the failure recurred. The vehicle was driven to the contact's residence and was not repaired. The contact referenced the manufacturer recall 2005110001 Sensotronic Brake Control as a possible solution however, the VIN was not included in the recall. The manufacturer was notified of the failure and the contact was referred to the NHTSA Hotline for assistance. The failure mileage was approximately 149,000.

Mileage: 149,000

20240205SERVICE BRAKES, HYDRAULIC

The contact owns a 2006 Mercedes-Benz E350. The contact stated that upon depressing the brake pedal, there was a beeping sound coming from the vehicle with a message stating "Stop, Reduced Braking Power, Depress Brake Pedal Fully" displayed on the instrument panel. The contact pulled over to shoulder of the road. Due to the failure, the vehicle was towed to the residence. The dealer was notified of the failure and the contact was informed that the vehicle was not covered under NHTSA Campaign Number: 05V133000 (Service Brakes, Hydraulic) which was linked to the failure. The manufacturer was also notified of the failure and the contact was referred to the NHTSA Hotline for assistance. The vehicle was not repaired. The failure mileage was approximately 177,000.

Mileage: 177,000

20231230ENGINE

Certain Mercedes-Benz models 2005- 2007 M272 V6 and M273 V8’s have faced or are facing issues regarding the balance sprocket in which drives the camshaft and crankshaft of the vehicle. Mercedes-Benz had made a decision to make certain engine components out of soft metals, when such metals are not adequate in handling the stress of the engine. In particular, in many cases, the balance sprocket was made with inadequate materials and gradually deteriorated to the point in which it could not engage the timing chain and cause camshaft-crankshaft misalignment. I personally did not experience such failure yet but it is more of a concern as this is a common issue , the repair is quite substantial and the failure can damage the engine even more

20231031ENGINE

Engine codes P0016 and P0017 reads cam shaft and crank shaft correlation it is everywhere on the internet and on the Mercedes Benz Forum.This is a know problem that Mercedes has ignored. its on all 2004 thru 2008 vehicles with the 3.5 engine. Calls for a balancer shaft replacement. This should definitely be a recall issue.The industry knows that is was poorly manufactured part. Your help with rectifying this issue would greatly help the and restore the reputation of Mercedes and restore faith in Mercedes Benz owners. My vehicle is a 2006 E350 4 Matic with only 113,634 miles

20230319FUEL/PROPULSION SYSTEM

PZEV fuel tank leaks at top but is not repairable. Replacement requires complete tank replacment which is not economically feasilble. This forces owners to continue to operate vehicle with fuel leakage since repair of the tank is not possible. In older models a simple gasket change would resolve such leaks, in the PZEV tank leaks can not be repaired and thus are left uncorrected. Many of these vehicles are now owned by minority owners who are unable to pay $5000 to repair a defective design. MB refuses to support owners.

20221227ENGINE

Driving the vehicle on several occasions on Interstate 66 and the vehicle spontaneously went into limp mode. Now we find out it's a balance shaft issue and is a known problem from Mercedes in the M272 engines for our 2006 E350 4-matic. They evidently used balance shafts with materials that were too soft, resulting in premature wearing of the balance shafts with all of the M272 engines produced during this time having the problem. There was a previous class action lawsuit, which Mercedes settled, however, the consumers were not adequately notified and no recall was ever issued for the cars. Now we have 2nd or 3rd owners having these problems that didn't get a notice and have no idea there is a huge expensive and dangerous problem with their vehicle. On I-66 traffic moves at 70 mph (regular lanes) or 75 mph (express lanes). Having the vehicle spontaneously go into limp mode because of this engine issue is dangerous and could have caused a fatal accident on multiple occasions for us. Merc

20221214FUEL/PROPULSION SYSTEM

I recently started smelling gas in my car after refueling. I was told by my mechanic that Mercedes was replacing fuel pumps and fuel tanks free of charge . Mercedes Benz customer care has advised this isn't so. This is an expensive repair and I am hoping Mercedes Benz can cover the cost of this repair and if not, offer substantial assistance.

20221205ENGINE

We just purchased a 2006 Mercedes for our teenage sons and had a dealer look at it before we purchased it. They told us there were a couple of codes that were worth watching but that it wasn’t anything significant right now. After the car started jerking and shaking while driving it, we brought it in to dealership where they told us it had a common code for Mercedes in this timeframe P0016. Repair estimate is nearly $5000 to replace timing chain and balance shaft, or a new engine which would be roughly the same. After researching on my own upon being told this code, I found all of the information about the class action lawsuit and settlement, which of course we are too late to be a part of. The dealer said there is a potential that the car could just seize up at some point, so I don’t want my young sons to be out on the road when that happens. I am very frustrated and upset that this wasn’t a recall since it apparently affected a huge amount of vehicles manufactured within this t

20221111FUEL/PROPULSION SYSTEM

In June 2017, I received a letter from Mercedes-Benz of America informing me that the warranty of the fuel system in my vehicle is extended to 15 years. In that same year, I had my whole fuel tank replaced by an authorized Mercedes Benz dealer in San Jose, California due to strong smell of fuel by the rear wheel well on the driver side of the car. The repair was fully cover by MB-America under this extended warranty. On November 3, 2022, I experienced the same fuel smell from the same place of the car (i.e., driver side rear wheel well) and was told that the repair will not be cover at all, even though the fuel system in my car is only 5 years old. I am writing to suggest that you impose a 15 years warranty on the fuel leak replacement parts. MB needs to stand behind their product if it was their OEM parts and done by their authorized dealer. In my case the new fuel smell was due to a cracked Fuel Pump Assembly (Part # 211 470 60 94) which was found in the brand new fuel tank installed

20220822SERVICE BRAKES

February 22, 2022 I was driving from Memphis, TN to Flower Mound,TX. It was raining really bad and once I got to Texas on University Ave. My brakes went completely out. I had to shut the car off to stop. Shortly after I heard about a recall involving this same matter but it was for 2006 Mercedes SUV. However after reading the recall the same thing happened to me E350. I had to pay over $2000 on this repair. I feel I am entitled to be refunded. I also had to get the car towed home. I have tow record and repair record. And you should be able to research the weather on that date from Memphis to Texas. Please give me a response at [XXX] or email me at [XXX]. INFORMATION Redacted PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6).

20220819FUEL/PROPULSION SYSTEM

THE CAR WOULD NOT START AS THE FUEL PUMP WAS FAULTY AND IS PART OF THE TANK DESIGN. MBZ KNEW OF THE PROBLEM BECAUSE THEY REPAIRED OR REPLACED SOME OF THE CARS BUT I WAS NEVER NOTIFIED TILL THE PROBLEM. IT COST ME UNDER $3,800 TO REPAIR AND REPLACE THE GAS TANK EVEN THOUGH THEY REPAIRED A LOT OF CARS. MY REPAIR WAS FINISHED ON 05/14/18. I PAID $3,409.33 FOR THE REPAIR AND I WANT TO BE REIMBURSED FOR IT. I FILED A COMPLAINT BACK IN 05/31/2018 UNDER THE COMPLAINT NUMBER [XXX]. I NEED HELP TO GET MY MONEY BACK. THIS WAS A BAD DESIGN ON THEIR PART. THANK YOU, [XXX] THE CAR WOULD NOT START FUEL PUMP FAULTY AND IS PART OF GAS TANK BAD DESIGN COST ME CLOSE TO $3800, SOME PAID BY MBZ. MBZ REPLACED 2009 GAS TANKS FOR FREE UNDER WARRENTY BUT WOULD NOT DO MINE. THIS IS A BAD DESIGN THEY SHOULD HAVE TOLD ME ABOUT IT SO I WOULD NOT BUY THE CAR. IT IS STUPID TO HAVE TO REAPLCE GAS TANK IN ORDER TO REPLACE A FUEL PUMP IN 2012 I HAD GAS LEAKAGE FROM THE SAME AREA AND I PAID TO FIX IT THEY SHOULD HAVE

20220720SERVICE BRAKES

Brake failure at 40 mph. RED CAUTION light on : "STOP Reduced braking power Depress brake pedal fully"

Mileage: 140,000

Compare 2006MERCEDES-BENZE350 to Similar Vehicles

NHTSA Investigations

Frequently Asked Questions

How many complaints does the 2006 MERCEDES-BENZ E350 have?
The 2006 MERCEDES-BENZ E350 has 482 NHTSA complaints, 20 crashes, 13 fires, 36 injuries, and 3 deaths reported.
Are there any recalls for the 2006 MERCEDES-BENZ E350?
Yes, the 2006 MERCEDES-BENZ E350 has 4 recall(s). The most common affected component is VISIBILITY:SUN/MOON ROOF ASSEMBLY. Recalls are issued by NHTSA and manufacturers must provide a free remedy.
What are the most common problems with the 2006 MERCEDES-BENZ E350?
The most-complained component for the 2006 MERCEDES-BENZ E350 is FUEL/PROPULSION SYSTEM with 144 complaints. Other frequently reported areas include FUEL SYSTEM, GASOLINE and ENGINE.
Is the 2006 MERCEDES-BENZ E350 safe to buy?
Review the complaint history, crash and fire reports, safety ratings, and recall status on this page to make an informed decision. No NHTSA crash test rating is available for this model year. Compare with other model years using the links above.
Where does this data come from?
All complaint, recall, and safety rating data is sourced from the National Highway Traffic Safety Administration (NHTSA). Complaints are filed by vehicle owners through NHTSA's Office of Defects Investigation.

Vehicle Safety Guides

Data as of 2025. Sources: NHTSA Office of Defects Investigation (ODI) complaints database, NHTSA recall campaign API, NHTSA NCAP crash-test ratings, and NHTSA FARS for fatality cross-reference.